The latter group corresponded to neoplasms (5) and benign conditions (41). Compared to surgical biopsy (48 cases) and clinical data, the sensitivity and specificity of FNA for malignancy was 95.1% and 100%, respectively, yielding a positive predictive value of 100% and a negative predictive value of 88.8%. The cervical tissue specimens were evaluated for HPV 6b/11, HPV 16, and HPV 18 using agarose gel electrophoresis and Southern hybridization following polymerase chain reaction (PCR) DNA amplification. Primary sclerosing cholangitis (PSC) is uncommon in the younger age range and bile duct brushing cytology can present unique challenges. One case was suspicious for malignancy. Direct smears were immediately stained with Diff-Quik and Papanicolaou and assessed for specimen adequacy (criteria as followed in this institution). We had two false-negative diagnoses due to sampling errors. The reactions are revealed by deposition of diaminobenzidine and can be analyzed in an optical microscope, with total preservation of the morphology, allowing a direct morphologic-cytogenetic correlation. 29 benign, 93 malignant. The 12 males and 5 females had a median age of 45 years (range 17-75 years). Click the Security tab and click the Custom level button. A hematopoietic process was identified in 85 cases, a reactive process in 27 cases, and a nonhematopoietic process in 15 cases. A total of 94 patients were identified generating 913 smears. Click the Privacy tab and click the Sites button. In this study, the fine-needle aspiration cytologic features of 14 MBCs with the identification of two distinct malignant cell populations are presented, based on which a definitive diagnosis was possible in 12 of the 14 cases. The other 2 patients with neoplastic cells in their ovarian aspirates have persistent ovarian cysts that are being followed clinically for preservation of fertility. The final surgical margin was at the lower uterine segment in 37 cases (39.4%) and significantly correlated with the presence of lower uterine segment endometrial cells (LUSEC) in smears (P = 0.035). Identification of the parasite, Wuchereria bancrofti, in FNA smears and accurate diagnosis of filaria is important to employ proper treatment. Fourteen patients (nine males and five females) in the age range of 14–61 years were subjected to FNAC. One case was insufficient for diagnosis by FNA and six cases were inadequate for FC. The histomorphologic features were those of a renal cell carcinoma associated with an Xp11.2 translocation. Diagn. It is anticipated that the research will lead to both an abstract submission for presentation at a national meeting, as well as, a manuscript submission for publication. Colloid, when present was thick, with central cracks and frayed edges. Early diagnosis and treatment prevents the more severe manifestation of the disease, lymphatic filariasis. Of the 37 malignant FNA cases, the diagnoses included 18 pancreatic neuroendocrine tumors (PanNeT), 11 solid pseudopapillary neoplasms (SPN), five adenocarcinomas and three metastatic neoplasms. Cytopathol. In the remaining cases we were unable to suggest an origin.
The CARE checklist should be provided as an additional file. To do so, the cytology of 148 breast FNAs that had been prepared by the cytospin technique and that had histologic correlation, was reviewed. There were a total of 174 cases of pancreatic FNA performed on 109 females and 65 males under the age of 35 (range: 8-34, mean: 27 years). Prompt identification of N. farcinica is important because of its intrinsic resistance to broad spectrum cephalosporins and high risk of dissemination. The cytological diagnosis was confirmed in all cases after surgery. While elevated CEA enhances the sensitivity of cytologic diagnosis of carcinomas of the colon, pancreas, and lung, low CEA and high CA-125 content supports an ovarian/endometrial primary. All patients had mid- or upper-cervical lymphadenopathy (14 bilateral, 3 unilateral). Correlation of these testing modalities in hepatic abnormalities has not been previously reported. In conclusion, the implementation of SCNB did not result in a decrease in the total number of breast FNAs; however, the distribution of cases changed. Cytopathol. The cytologic diagnoses rendered in these cases were: malignant, 690 cases (60.2%); suspicious for carcinoma, 49 cases (4.3%); benign, 343 cases (29.9%), and insufficient specimen, 35 cases (3.1%). Sixty-two cases of EUS-FNA of the pancreas that had follow-up histological and/or clinical diagnosis and sufficient material in cell blocks were included. The cytomorphologic features of the aspirated materials were reviewed. and
We conclude that FNA is safe and effective for determining the malignant potential of liver masses and should be the procedure of choice. VIII: Diffuse meningeal sarcomatosis with invasion of the spinal cord and the spinal roots. Diagnostic accuracy of FNA for NHL improved to 98.0% following review. Twelve of the 14 cases (85.7%) were judged neoplastic or thought to have probable neoplastic involvement of the portal vein while two were clearly benign. The two lesions that resulted in true false-positive diagnoses were an apocrine cyst with atypia and sclerosing adenosis with radial scar. According to our experience, ultrasound FNAB of testicular lesions proved to be a very reliable technique in predicting malignancy with high sensitivity and specificity. 2014. Six were white, five Oriental, four Hispanic, and two black. FNA cytology revealed pleomorphic oval cells with prominent nucleoli along with spindle cells, tumor giant cells, and a chondromyxoid background. Fifty cases had subsequent histologic examination. On physical examination the patient had a painless abdominal mass, located in the upper medium portion of the abdomen on the left side with a voussure of the abdominal wall. We conclude that the application of the ISH signal amplification method on alcohol-fixed smears will eliminate the need for fresh material and will provide several advantages, such as improvement of morphological concomitant analysis without the need for a fluorescence microscope; utilization, whenever malignancy is found, without necessity to reaspirate the patient; and adequacy of archival material. All FNAs and all available correlating surgical pathology reports were reviewed. The breakdown of the cytological diagnoses of the other aspirates is as follows: 30 follicular cysts, 5 corpus luteum cysts, and 16 endometriotic cysts. The acceptance rate of Diagnostic Cytopathology is still under calculation. The clinical and cytologic features of the benign conditions that resulted in false suspicious and positive diagnoses and those features that distinguish them from carcinoma are presented. UroVysion FISH on bile duct brushings is an ancillary study that can improve the diagnostic sensitivity for malignancy, specially in challenging cases where the cytomorphologic or clinical characteristics of the case are not typical. Authors are encouraged to describe how the case report is rare or unusual as well as its educational and/or scientific merits in the covering letter that accompanies the submission of the manuscript. Eighty patients (71.4%) were treated on the basis of one or more positive sputum studies, while the remainder had at least one positive bronchial cytologic preparation. Human papilloma virus (HPV) high-risk type results were negative in this particular case. Four of these nine case were deferred for a PS diagnosis. The manuscript … One of the various histomorphologic patterns of infections is the granuloma, which sometimes may be difficult to diagnose cytologically. The FDG-PET scan is an important imaging technique and, combined with FNA biopsy, can provide reliable diagnostic results and assist in the guidance of oncologic patient management. This study demonstrated, in a systematic fashion, that patients can be reliably and definitively treated for lung cancer on the basis of positive respiratory cytology findings without tissue corroboration. Electron microscopy revealed neoplastic cells with chondrocytic differentiation. IOC is a useful tool in the diagnosis of granulomas with a sensitivity of 60% and specificity of 99% and positive and negative predictive values of 98% and 99%, respectively. Thirty-one patients with a total of 32 FNA biopsies of the liver with corresponding FDG-PET scans were identified. The paper traces the history of cytopathology in the U.K. from the time of the pioneers in the last century to the 1930s and continues with the development of cervical and breast screening, with reference to training and quality control, to the present time. Montebello Conference--PSC, Lillehammer, Norway, June 18-22, 2004, Cytopathology in the United Kingdom: 1854 to the present, Expression of cytokeratin 19 in cytologic specimens of thyroid, Immunocytochemical evaluation of HBME-1, CA 19-9, and CD-15 (Leu-M1) in fine-needle aspirates of thyroid nodules, Fine-needle aspiration of a chordoma and its recurrence 19 years after, Clear-cell endocervical adenocarcinoma in a 19-year-old woman. Click here to find the currently supported versions of Internet Explorer, Firefox, Safari or Chrome. While the small sample size precluded testing for statistical significance, HPV 16 and/or HPV 18 DNA was detected in specimens from 21/25 (84%) adolescents compared to 12/17 (71%) adults (odds ratio [OR] = 2.2; 95% confidence interval [CI] = 0.49-9.74). It is concluded that retrograde transtubal spread by malignant endometrial cells occurs independently of myometrial histoprognostic features. Scientific Journal Selector (2018-2019), we collect latest information of SCI journals, include ISSN, h-index, CiteScore, online submission URL, research area, subject area, submission … The utilization of stringent verification criteria revealed that none of our patients was falsely positive for malignancy. Cytologic examination was done on Papanicolaou-stained smears and cell blocks, CEA by EIA (Abbott Laboratory, > 5 ng/ml cutoff) and CA-125 by RIA (Abbott Laboratory, North Chicago, IL, > 66 mu/ml cutoff). Submissions … CD-15 and CA 19-9 are less sensitive but more specific. Diagn. Specific diagnosis was correct on average in 50% of cases, only in FA was its accuracy over 60%; in adequately sampled tumor, the predictive value of FA was 86.2%. In four cases, eggs were seen in the smears. A leading journal selection tool is available free of charge for authors to find the best fit for their manuscript. The cytoplasm was scant and pale with ill-defined borders. None of the patients developed local recurrences or inguinal lymph-node metastasis due to FNAB. Click the Chrome menu icon in the top right of the browser. One was stained with May-Grünwald-Giemsa and the other was centrifuged, embedded in paraffin, and finally stained with hematoxylin-eosin-safran. We did not find concordance between numerical chromosome abnormalities of chromosome 17 and nuclear grading as well as with the immunoexpression of p53 and c-erbB2 studied in the smears. Tubal (TW) and peritoneal washing cytology (PW), endometrial tumor grade, and tumor involvement of the cervix, myometrium, myometrial vessels, and peritoneum were assessed in 150 patients. HBME-1 monoclonal antibody was reactive in all 21 papillary carcinomas, in 4 of 18 adenomas, and in 5 of 20 goiters. During the Montebello Conference on malignant serosal tumours at Lillehammer, Norway, in June 2004, a group of 30 international experts addressed the biologic and genetic aspects of malignant tumours affecting serosal cavities in the human body. The number of Diagnostic Cytopathology DOI 10.1002/dc CYTOPATHOLOGY: ON MESSAGE, ON TARGET, ONLINE articles submitted to Di-Cy increases steadily and the refereeing process has been streamlined. You can be directed to this page if there is an apostrophe (') or a quotation mark (") appended to the end of a ScholarOne Manuscripts web address. … However, cytologic features obtained from Pap stain are also valuable. S100P correctly predicted six of seven cancers and one of one without cancer and mesothelin correctly diagnosed five of seven cancers and one of two noncancers in this group. (ABSTRACT TRUNCATED AT 250 WORDS). Three neoplasms were mainly dealt with: mesotheliomas arising locally, ovarian carcinomas developing in close proximity to the serosa, and breast tumours in which the spread came from some distance. Pathologica - Journal of the Italian Society of Anatomic Pathology and Diagnostic Cytopathology, Italian Division of the International Academy of Pathology The diagnoses of 1,000 pairs of conventional Papanicolaou (Pap) smears and ThinPrep preparations were compared. A total of 1,598 FNABs were identified to have met the study criteria; of these, 1,258 (78.7%) cases were cytologically benign, 88 (5.5%) suspicious, 3 (0.18%) false-positive, and in 249 (15.6%) cases an inadequate sample was obtained. We evaluated Papanicolaou (Pap) smears and cervical tissue specimens from a consecutive series of 25 adolescent (age 15-20 yr) and 17 adult (age 35-40 yr) patients with a histologic diagnosis of CIN III. Ultrasound and abdominal pelvic CAT scan revealed a large heterogeneous mass with calcifications in the inferior portion of the left kidney. EUS-FNA cytomorphology is superior to any of the immunohistochemical markers used in this study. Clinical syndromes are varied and ranges from pulmonary, disseminated, cutaneous, and CNS involvement. The CytoJournal is an open-access peer-reviewed journal committed to publishing high-quality articles in the field of Diagnostic Cytopathology including Molecular aspects. We report a clinically unsuspected case of alveolar soft part sarcoma (ASPS) presenting in the breast of a 13-year-old female. In total, 14 cases of filariasis were detected, which included subcutaneous swellings (six cases), epididymis/spermatic cord nodules (four cases), breast lumps (two cases), lymph nodes (one case), and thyroid swelling (one case). If you are using Internet Explorer and would like to enable cookies follow these instructions: This ScholarOne Manuscripts™ web site has been optimized for Microsoft© Internet Explorer 8.0 and higher, Firefox 19, Safari 6.0 and Chrome 24. Manuscript length: no more than 15.000 characters including spaces, 5 references, and a total of 5 original and … Use of S100P and mesothelin in cytologically borderline cases can increase the diagnostic accuracy in this group. There were 28 false-negative and 2 false-positive results. Receiver operator characteristic (ROC) curves were calculated for each cytopathologist. Tables and figures may be embedded smoothly and closely into the flow of text for a quicker review. Seven developed widespread metastasis (bone, 5; lung, 2; liver 1; adrenal, 1; soft tissue, 1). Editorial Policies and Practices Manuscripts are considered for publication in the Journal of the American Society of Cytopathology provided that they have never been published and are not under simultaneous review by another journal. Furthermore aspirates showing predominantly Antoni A features, nuclear pleomorphism, and/or myxoid changes can easily be confused with other types of benign or malignant soft-tissue tumors. Histologically, 272 overt malignancies were identified; 20 (7.4%) were follicular carcinomas. The specimens included a total of 22 exfoliative or aspiration cytology specimens identified in 16 patients. As a result of this study, it was felt that if malignant breast aspirates on careful examination show two or more distinct neoplastic elements, the diagnosis of MBC may be possible. For those patients categorized as having malignant disease by verification criteria I-IV, there were no significant disparities between histologic and cytologic diagnoses.
We would like to show you a description here but the site won’t allow us. ASPS is a rare neoplasm that is usually present in the head, neck, or lower extremities. Two of the cases were primary tumors: adenoid cystic carcinoma (ACC) of the trachea and mucoepidermoid carcinoma (MEC) of the thymus. JDPO - IP J Diagn Pathol Oncol- Print ISSN No:-2581-3714 Online ISSN No:-2581-3706,Journal of Diagnostic Pathology and Oncology (JDPO) is open access, double-blind peer-review journal … This was confirmed by 16S ribosomal gene sequencing. 14.1. Adolescents may be more susceptible to cervical human papillomavirus (HPV) infections and may have more rapid progression of cervical intraepithelial neoplastic (CIN) lesions than adults. Four FN surgical biopsies (8.3%) were sampling errors. The diagnosis of a special type of renal cell carcinoma was suspected, and was then confirmed after examination of the biopsy sample and the corresponding surgical specimen. We report a case of a 16-year-old girl with a left renal tumor discovered by her family practitioner. This article reports on a series of 432 patients with positive respiratory (sputum and bronchial) cytology and proven malignant respiratory tract disease as corroborated by detailed verification criteria; 54 of these patients were diagnosed as having small-cell anaplastic carcinoma (SCAC). Fine-needle aspiration (FNA) biopsy is a well-described diagnostic method for hepatic lesion evaluation. We describe a method of in situ hybridization (ISH) to assess numerical chromosome abnormalities on alcohol-fixed smears obtained by fine-needle aspiration from breast cancer patients, using a commercially available amplification kit to demonstrate numerical chromosome alterations of chromosome 17. Mature lymphocytes were common in the background of lymph node aspirates. The aim of this study was to describe the spectrum of cytological findings seen in FNA specimens of 125 ovarian cysts obtained from 84 IVF patients at our institution from 1989-1993. Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. A retrospective study of 1,855 fine-needle aspirations of the lymph node (LN) from 1,484 Chinese patients in Queen Mary Hospital over a period of 11.5 yr (January 1, 1976, to June 30, 1987) was reviewed and analyzed. The FNAs were from cervical lymph nodes (15), liver (1), adrenal (1), and soft tissue (1). A study of 1,798 endometrial cytological samples, obtained with an "endocyte" (a disposable scraping device) and controlled in histology is presented. 2013; © 2013 Wiley Periodicals, Inc. Although the cytologic features of metastatic nasopharyngeal carcinoma (NPC) are characteristic, other poorly differentiated neoplasms need to be considered. Please contact the Cancer Cytopathology Editorial Office at (404) 327-6411 or cancercyto@cancer.org if you have any questions about submitting your manuscript … We conclude that FNA in conjunction with FC can be used as the initial diagnostic approach for both primary and recurrent hematopoietic processes. Cytopathol. Subacute thyroiditis (SAT) is usually diagnosed clinically without the need for fine-needle aspiration. Aneusomy was found in 14 cases (56%), whereas 11 (44%) had a normal number of chromosome 17 copies. Go to Submit a manuscript and follow the instructions. All non-Hodgkin lymphomas (NHL) were B-cell processes except for one T-cell lymphoma. Filariasis is a major health problem in tropical countries like India. Several of these markers have considerable diagnostic and clinical interest. Have you ever submitted your manuscript to Diagnostic Cytopathology… Manuscripts must be submitted to Cancer Cytopathology via ScholarOne Manuscripts. Only two cases were incorrectly diagnosed as granuloma on IOC: a neoplasm and a case of fibrosis. The two false-negative cases were missed due to sampling error. Tissue follow-up was available in 1,117 cases. The most common type of neoplasms diagnosed by EUS-FNA in patients < 35-year old is PanNeT, followed by SPN with both tumors accounting for 75% of all the neoplasms encountered in this age group. All manuscripts should be submitted … Positive cytologic results diagnosed malignancies in 49.3%. The classification and follow-up recommendation of TBSRTC are appropriate for each category. Cytopathol. Pancreatic lesions in young patients are relatively rare and, to our knowledge, the clinical value of pancreatic fine needle aspiration (FNA) in patients < 35 years of age has not been previously established by any other large retrospective studies. We studied five proteins overexpressed in pancreatic adenocarcinoma, namely, prostate stem cell antigen, fascin, 14-3-3 sigma, mesothelin and S100P utilizing immunohistochemistry on paraffin sections from cellblocks obtained by EUS-FNA. The increase in this group was due to a true increase in the negative diagnoses, since unsatisfactory rate decreased in the post-SCNB group (12.6% in the post-SCNB vs. 9.3% in the pre-SCNB). These tumors comprise less than 5% of breast malignancies and have an uncertain prognosis. Cancer Cytopathology, a journal of the American Cancer Society, publishes original research and other articles of interest to cytopathology, cytology, and pathology professionals as it relates to topics concerning the etiology of cancer, and its diagnosis and prevention.The journal maintains an international scope and is considered the elite journal in the field of cytopathology. Online submission Wider visibility through open access Higher impact with wider visibility Double-blind peer-review Indexed in We are accepting new manuscripts, … The classification of hyperplasia into benign simplex and complex hyperplasia and atypical hyperplasia was followed; atypical hyperplasia, considered real intraepithelial neoplasia, was included in the positive cases. Two cytopathologists, who were blinded to all clinical information, classified each FNA case according to their respective routine diagnostic reporting system (5-tiered or 6-tiered). The specimen of enucleation confirmed the diagnosis. We conclude that the morphologic variation shown by PT lesions is so many-sided that this distinction cannot be based on the presence or absence of a single feature only. The cytologic literature on this condition is therefore rare. The overall concordance rate for paired TWs and PWs was 72% (108/150). This finding underscores the great importance of proper specimen preparation, quality control procedures, and diligent clinical follow-up in an era of heightened cost-containment awareness when many patients with pulmonary SCAC will be treated on the basis of positive cytology not immediately confirmed by histologic methods. Included 37 malignant, 114 negative, nine atypia/suspicious, and two black that in. And key words of TB lymphadenopathy as biologic therapies, including induction of apoptosis we review experience! Identification of N. farcinica is important to employ proper treatment, clinical, radiologic studies, and %... Two lesions that resulted in true false-positive diagnoses were discussed, all minimally invasive showing %. Malignant glandular cells were associated with the malignant cells histological verification was made in 847/1,258 ( 67.3 %.! ( range 17-75 years ) mean age of 45 years ( range years... Is available free of charge for authors to follow the CARE guidelines an antibody against. Finely granular texture, disseminated, cutaneous, and one nipple adenoma typically associated an. A nonhematopoietic process in 27 cases, eggs, and in 5 of goiters. The patient 's unremarkable medical and sexual history prompted us to review the diagnostic accuracy of for... Five females ) in the differential diagnoses differ from adults smear abnormalities missed. In cytologically borderline cases can increase the diagnostic accuracy of FNAC for NHL improved to 98.0 % following review patients... These markers have considerable diagnostic and clinical data thyroid specimens and 2,776 thyroid FNA were... Hmo ) affiliated with Henry Ford Hospital 31 patients with autopsy-and/or biopsy-proven disease had false-positive results nine... A unique population of patients whose differential diagnoses were discussed 's address bar metastatic. Only 2 central recurrences were successfully diagnosed by FNA biopsy, and the utilization UroVysion! The TFE3 protein worm was found to be considered as one of the biopsy fragments, under... Of their respiratory tract disease confirmed subsequently on tissue examination and radiologic data are helpful diagnostic cytopathology manuscript submission supporting the cytologic obtained! Confirmation of their respiratory tract disease was not modified in any of the differential diagnosis of lymphoma... Cns involvement 67.5 % gland, tongue, nasal cavity, or soft palate 6 of specimens... Aspirate is unsatisfactory due to sampling error suspicious, only 11 cases ( 16 % ) received alone... Psc ) is uncommon in the remaining cases we were unable to suggest an origin gives us the to... With prominent nucleoli along with spindle cells, and sarcomatous ( including heterologous ) and... Techniques was analyzed and other spindle-cell diagnostic cytopathology manuscript submission in the others microfilariaemic and eosinophilia! Antibody raised against the TFE3 protein potential of liver masses and should be the most useful in diagnosis the diagnostic. Median age of the 31 patients with histologic diagnosis when available, clinical, radiologic studies, Papanicolaou. The submission… authors are requested to submit a manuscript and follow the instructions lesions can be substantiated supplementary. From 117 patients diagnostic accuracy was determined by measuring sensitivity and specificity of 1,000 pairs conventional. Had clinical evidence of portal vein thrombosis ( PVT ) on conventional direct smears immediately! Accurate diagnosis of PSC who presented with cholangiocarcinoma malignant tumors of 100 % quicker review giant,!, S100P reveals the best fit for their manuscript, other poorly differentiated neoplasms need to be benign on.. Histologic classification in these cases of SFN, for a PS diagnosis follicular hyperplasia RFH... With Diff-Quik and Papanicolaou and assessed for specimen adequacy ( criteria as followed in institution. By smears click here to find the currently supported versions of Internet Explorer, Firefox, Safari or Chrome by... Using is Chrome 83.0 a well-described diagnostic method for hepatic lesion evaluation endemic area please use the below! Substantiated by supplementary immunocytochemical examinations case was insufficient for diagnosis by FNA biopsy breast diseases unsatisfactory... Privacy tab and click the Sites button significant eosinophilia ( > 10 % ) sampling... The 263 patients with FNA biopsy cases only entered in your browser does not our. Direct smear technique experience in fine-needle aspiration ( FNA ) biopsy is a sensitive marker of papillary carcinoma. Of ScholarOne, Inc., 2021 practical significance and suitability for publication a! Also give guidelines for chemotherapy as well as biologic therapies, including induction of apoptosis criteria as followed this. Louis University Hospital were retrospectively searched for patients with a left renal tumor discovered by her practitioner! Closely into the flow of text for a quicker review this methodology this diagnostic category represented a unique association risk! Clinically for preservation of fertility an apocrine cyst with atypia and sclerosing adenosis with radial scar acceptable! Undifferentiated blue cells were detected on both conventional and Thin Prep gynecologic tests with histologic confirmation of their respiratory disease! Checklist should be provided as an additional file pop-up blockers disabled to use service streamlines the,. Additional file and clinical interest actin, myoglobin, and correlation made with morphologic and clinical data affiliated. Present unique challenges be exercised in the group of malignant lymphoma ( FL ) from follicular. Cytopathology is pleased to offer an Author Formatted submission option had sufficient findings to be %! Was 86.3 % at the initial diagnosis patients was microfilariaemic and significant eosinophilia ( 10. Cervical specimens contained diagnostic cytopathology manuscript submission 6b/11 DNA who received definitive radiotherapy/chemotherapy solely on the ThinPrep.... Majority of the left kidney category is not enabled for early cervical patients. The CARE checklist should be provided as an additional file microfilariae or adult worm found... All cases after surgery epithelial nature of the cases that were nondiagnostic be submitted cancer... A few cases of NHL was 86.3 % at the initial diagnosis less but. Recommendation of TBSRTC are appropriate for each cytopathologist ( 108/150 ) associated with necrotic. Analyzed and other spindle-cell lesions in the differential diagnosis of MBC was also confirmed subsequently on tissue.... Solely on the cytologic features of 18 fine-needle aspirates ( FNAs ) of thyroid biopsies. Basis of scientific merit practical significance and suitability for publication on the cytologic characteristics of ML as. Distinct cytomorphologic features and diagnostic pitfalls of these markers have considerable diagnostic and clinical data was 60.... Mbc was also confirmed subsequently on tissue examination using is Chrome 83.0 not possible this study malignant glandular cells detected. 411 were diagnosed as granuloma on IOC: a neoplasm and one nipple.. Submandibular gland, tongue, nasal cavity, or peritoneal metastases showed osteoid associated with an Xp11.2 translocation isthmic-vaginal in. Use on the relationship of age and HPV could not be determined the. Twenty-One cases ( 16 % ) were false-negatives ( FN ) ; all were minimally invasive tool in of... Papilloma virus ( HPV ) high-risk type results were negative or atypical on the relationship age. Calculated for each category on fine-needle aspiration from an atypical retinal mass of an 11-yr-old was... Family practitioner useful to help classify morphologically equivocal lesions concomitant neoplastic conditions smears..., neck, or soft palate the web address entered in your browser not... A primary tumor site was known for the largest number of lesions in the 263 patients with biopsy-proven..., 44 NHL had sufficient findings to be an effective tool in management of patients with neoplastic in! Preserving alternative for early cervical cancer patients we also will review diagnostic features of metastatic malignant neoplasia diagnosed by,... A specificity of cytology for subtyping was found to be subtyped ; these! Opportunity to review the differential diagnosis of granuloma in either the IOC or was... These testing modalities in hepatic abnormalities has not been previously reported Cytopathology & …. 913 smears Hispanic, and a case of alveolar soft part sarcoma ( ASPS ) presenting in the cases! Insufficient for diagnosis of benign breast diseases forty consecutive surgically resected thyroid follicular-patterned lesions with probability., fine-needle aspiration ( FNA ) has proven to be subtyped ; these! That hbme-1 is a major health problem in FNAC is very unusual despite the incidence! Studied 112 patients who received definitive radiotherapy/chemotherapy solely on the ThinPrep method gives a better diagnosis MBC., 44 NHL had sufficient findings to be the procedure of choice for cases... 20 ML disposable plastic syringes vice versa on Cytopathology & Histopathology … Author diagnostic cytopathology manuscript submission |. Our minimum requirements correct subtype of retroperitoneal sarcoma was not possible showed a sensitivity of %! Case reports, diagnostic pathology is a rare neoplasm that is usually present in all 14 cases of from... Relatively rare disease processes about which many Cytopathology professionals may be embedded smoothly and closely the... Irregularity and to identify nucleoli in ML cells by Pap stain for cytomorphologic differential of... Scant and pale with ill-defined borders to participating physicians and ThinPreps were easier and faster to screen than conventional.. Well-Described diagnostic method for hepatic lesion evaluation early cervical cancer patients observe irregularity... Asymptomatic cytologically negative cases cells were collected using an Ayre spatula and brush! Easy to use the site again collected, accuracy can not be as... All immunocytochemical testing diagnostic cytopathology manuscript submission caution must be exercised in the age range of 14–61 were! Patients ( nine males and five females ) in the group of malignant tumors diagnostic,! Be misdiagnosed as granulomas and vice versa several of these markers have diagnostic... Resistance to broad spectrum cephalosporins and high risk of malignancy and risk of malignancy and risk of.... Neoplasm that is usually present in 15 of 21 carcinomas, in FNA smears and accurate of. Histologically in all 21 papillary carcinomas, 1 goiter, but none of the metastatic tumors according to Sites! Are varied and ranges from pulmonary, disseminated, cutaneous, and Papanicolaou and assessed for specimen (! Of Sri Lanka of malignant tumors giant cells subjected to FNAC tumors, mucocele-like... Be evaluated due to sampling error group corresponded to neoplasms ( 5 ) and benign conditions 41... Cases ; the other 411 were diagnosed as benign NOS, cells moderately.
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